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Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis

NCT02221570 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2014-10-06

No results posted yet for this study

Summary

Patients with cirrhosis often experience muscle cramps with varying severity. The mechanism of their occurrence is not yet understood. Muscle cramps in patients with cirrhosis are associated with significantly diminished quality of life.

The aim of the study is to assess the efficacy of baclofen in the treatment of muscle cramps in patients with liver cirrhosis.

Conditions

Interventions

DRUG

Baclofen

Baclofen, a derivative of gamma-aminobutyric acid, is a muscle relaxant and an antispastic agent. It was introduced in 1966 as a possible treatment for spasticity due to corticospinal tract lesions. Baclofen was also tested with promising results in the treatment of other medical disorders such as cluster headaches, gastroesophageal reflux disease,chronic hiccups and cough.

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Asem A Elfert, MD · Tanta Faculty of Medicine, Professor

  • Lobna A AboAli · Tanta Faculty of Medicine, Lecturer

  • Samah M Soliman · Tanta Faculty of Medicine, Lecturer

  • Ibrahim Shebl · Tanta University Hospitals, House Officer

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2014-11-30
Completion
2014-11-30

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02221570 on ClinicalTrials.gov