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Assessment Of Lipid Profile In Cirrhotic Patients

NCT04788173 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2022-05-19

No results posted yet for this study

Summary

Cirrhosis is defined anatomically as a diffuse process with fibrosis and nodule formation. It is the result of the fibrogenesis that occurs with chronic liver injury.

Lipoproteins are complexes of lipid and proteins that are essential for transport of soluble vitamins Liver cells play a serious task in the regulation of lipid metabolism. The principal location for lipoprotein and cholesterol synthesis is in the liver.

In healthy individuals, a compound equilibrium is preserved between utilization, biosynthesis, and transfer of lipid fractions.

Many diseases that affect the parenchyma can lead to changes in the structure of lipoproteins and transport throughout the blood.

Nevertheless, in cirrhotic patients, the metabolism of lipid is changed such that glycogen stores are significantly diminished, contributing to malnutrition and biolysis.

Conditions

  • Cirrhosis

Sponsors & Collaborators

  • Sohag University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2021-09-01
Completion
2021-09-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04788173 on ClinicalTrials.gov