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Minimally-invasive Non-surgical and Surgical Periodontitis Treatment

NCT03797807 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2025-06-08

No results posted yet for this study

Summary

To compare the efficacy of a modified minimally-invasive non-surgical periodontal therapy (MINST) approach with a surgical approach (M-MIST) in determining bone and clinical attachment changes in intrabony defects

Conditions

  • Periodontitis

Interventions

PROCEDURE

MINST

A non-surgical minimally invasive treatment protocol, named MINST, has been proposed for the treatment of periodontal intrabony defects, in order to minimize patient discomfort and maximize the healing potential

PROCEDURE

MIST

A minimally invasive surgical treatment protocol, named MIST, has been proposed for the treatment of periodontal intrabony defects, in order to minimize patient discomfort and maximize the healing potential

DIAGNOSTIC_TEST

GTI subgroup (Geometrical/Thermal Imaging)

Geometrical/Thermal Imaging

Sponsors & Collaborators

  • Queen Mary University of London

    lead OTHER

Principal Investigators

  • Luigi Nibali, PhD · Barts & The London School of Medicine & Dentistry, QMUL

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-20
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03797807 on ClinicalTrials.gov