Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

Summary

This pilot clinical trial studies gallium Ga 68-edotreotide (68Ga-DOTATOC) positron emission tomography (PET)/computed tomography (CT) in finding brain tumors in younger patients. Diagnostic procedures, such as gallium Ga 68-edotreotide PET/CT imaging, may help find and diagnose brain tumors.

Conditions

• Acoustic Schwannoma
• Adult Anaplastic Astrocytoma
• Adult Anaplastic Ependymoma
• Adult Anaplastic Meningioma
• Adult Anaplastic Oligodendroglioma
• Adult Brain Stem Glioma
• Adult Choroid Plexus Tumor
• Adult Craniopharyngioma
• Adult Diffuse Astrocytoma
• Adult Ependymoblastoma
• Adult Ependymoma
• Adult Giant Cell Glioblastoma
• Adult Glioblastoma
• Adult Gliosarcoma
• Adult Grade I Meningioma
• Adult Grade II Meningioma
• Adult Medulloblastoma
• Adult Meningeal Hemangiopericytoma
• Adult Mixed Glioma
• Adult Myxopapillary Ependymoma
• Adult Oligodendroglioma
• Adult Papillary Meningioma
• Adult Pilocytic Astrocytoma
• Adult Pineal Gland Astrocytoma
• Adult Pineoblastoma
• Adult Pineocytoma
• Adult Subependymal Giant Cell Astrocytoma
• Adult Subependymoma
• Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
• Childhood Choroid Plexus Tumor
• Childhood Craniopharyngioma
• Childhood Ependymoblastoma
• Childhood Grade I Meningioma
• Childhood Grade II Meningioma
• Childhood Grade III Meningioma
• Childhood High-grade Cerebellar Astrocytoma
• Childhood High-grade Cerebral Astrocytoma
• Childhood Infratentorial Ependymoma
• Childhood Low-grade Cerebellar Astrocytoma
• Childhood Low-grade Cerebral Astrocytoma
• Childhood Medulloepithelioma
• Childhood Supratentorial Ependymoma
• Meningeal Melanocytoma
• Newly Diagnosed Childhood Ependymoma
• Recurrent Adult Brain Tumor
• Recurrent Childhood Anaplastic Astrocytoma
• Recurrent Childhood Anaplastic Oligoastrocytoma
• Recurrent Childhood Anaplastic Oligodendroglioma
• Recurrent Childhood Brain Stem Glioma
• Recurrent Childhood Cerebellar Astrocytoma
• Recurrent Childhood Cerebral Astrocytoma
• Recurrent Childhood Diffuse Astrocytoma
• Recurrent Childhood Ependymoma
• Recurrent Childhood Fibrillary Astrocytoma
• Recurrent Childhood Gemistocytic Astrocytoma
• Recurrent Childhood Giant Cell Glioblastoma
• Recurrent Childhood Glioblastoma
• Recurrent Childhood Gliomatosis Cerebri
• Recurrent Childhood Gliosarcoma
• Recurrent Childhood Medulloblastoma
• Recurrent Childhood Oligoastrocytoma
• Recurrent Childhood Oligodendroglioma
• Recurrent Childhood Pilocytic Astrocytoma
• Recurrent Childhood Pilomyxoid Astrocytoma
• Recurrent Childhood Pineoblastoma
• Recurrent Childhood Pleomorphic Xanthoastrocytoma
• Recurrent Childhood Protoplasmic Astrocytoma
• Recurrent Childhood Subependymal Giant Cell Astrocytoma
• Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
• Recurrent Childhood Visual Pathway and Hypothalamic Glioma
• Recurrent Childhood Visual Pathway Glioma
• Untreated Childhood Anaplastic Astrocytoma
• Untreated Childhood Anaplastic Oligodendroglioma
• Untreated Childhood Brain Stem Glioma
• Untreated Childhood Cerebellar Astrocytoma
• Untreated Childhood Cerebral Astrocytoma
• Untreated Childhood Diffuse Astrocytoma
• Untreated Childhood Fibrillary Astrocytoma
• Untreated Childhood Gemistocytic Astrocytoma
• Untreated Childhood Giant Cell Glioblastoma
• Untreated Childhood Glioblastoma
• Untreated Childhood Gliomatosis Cerebri
• Untreated Childhood Gliosarcoma
• Untreated Childhood Medulloblastoma
• Untreated Childhood Oligoastrocytoma
• Untreated Childhood Oligodendroglioma
• Untreated Childhood Pilocytic Astrocytoma
• Untreated Childhood Pilomyxoid Astrocytoma
• Untreated Childhood Pineoblastoma
• Untreated Childhood Pleomorphic Xanthoastrocytoma
• Untreated Childhood Protoplasmic Astrocytoma
• Untreated Childhood Subependymal Giant Cell Astrocytoma
• Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
• Untreated Childhood Visual Pathway and Hypothalamic Glioma
• Untreated Childhood Visual Pathway Glioma

Interventions

RADIATION

gallium Ga 68-edotreotide

Undergo gallium Ga 68-edotreotide PET/CT

PROCEDURE

positron emission tomography

Undergo gallium Ga 68-edotreotide PET/CT

PROCEDURE

computed tomography

Undergo gallium Ga 68-edotreotide PET/CT

OTHER

laboratory biomarker analysis

Correlative studies

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• Ride for Kids

  collaborator UNKNOWN

• Sue O'Dorisio

  lead OTHER

Principal Investigators

• M. Sue O'Dorisio, MD, PhD · University of Iowa

Study Design

Allocation

NA

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

6 Months

Max Age

29 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-09-30

Primary Completion

2017-03-31

Completion

2017-03-31

Countries

• United States

Study Locations