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A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors

NCT02006407 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2016-12-30

Study results available
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Summary

This is a pilot study to assess the changes in white matter, in the brain, in response to radiation therapy and correlate these changes with later declines in cognitive function.

Conditions

  • Brain Tumor, Primary

Interventions

RADIATION

Cranial Radiotherapy

Standard cranial radiotherapy administered dependent upon patient and brain tumor type.

DEVICE

MRI with Diffusion Tensor Imaging (DTI)

Magnetic Resonance Imaging (MRI) with Diffusion Tensor Imaging (DTI)

BEHAVIORAL

Neuro-cognitive Testing (CogState)

CogState is a computerized software testing system that offers various cognitive assessments based traditional expansive neurocognitive tests.

Sponsors & Collaborators

  • University of Michigan Rogel Cancer Center

    lead OTHER

Principal Investigators

  • Carl Koschmann, M.D. · University of Michigan Rogel Cancer Center

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
6 Years
Max Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2015-08-31
Completion
2015-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02006407 on ClinicalTrials.gov