Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
NCT02171988 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2018-04-18
Summary
The purpose of the study is to investigate effect of medical treatment and prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
Conditions
- Postural Orthostatic Tachycardia Syndrome
Interventions
- DRUG
-
Propranolol
Start propranolol 10mg bid, and then dose up to 20mg bid after one month if tolerable
- DRUG
-
Bisoprolol
Start bisoprolol 2.5mg qd P.O, and then dose up to 5mg qd. if tolerable
- DRUG
-
Propranolol+pyridostigmine
Start propranolol+pyridostigmine 10mg bid +30mg bid, and then dose up to 20mg bid+30mg bid. if tolerable.
- DRUG
-
Bisoprolol+pyridostgmine
Start bisoprolol+pyridostgmine 2.5mg qd+30mg bid, and then, dose up to 5mg qd+30mg bid. if tolerable
Sponsors & Collaborators
-
Seoul National University Hospital
lead OTHER
Principal Investigators
-
Kon Chu, MD, PhD · Seoul National University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 15 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-03-31
- Primary Completion
- 2016-02-29
- Completion
- 2016-12-31
Countries
- South Korea
Study Locations
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