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Nebivolol in the Supine Hypertension of Autonomic Failure

NCT01044693 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2015-05-01

Study results available
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Summary

The purpose of this study is to evaluate the effect of the antihypertensive drug, nebivolol (Bystolic), compared to metoprolol (Lopressor) and sildenafil (Viagra) on blood pressure in patients with autonomic failure and supine hypertension.

Conditions

Interventions

DRUG

Placebo

Placebo capsule

DRUG

Nebivolol 5 mg

Nebivolol 5mg single oral dose

DRUG

metoprolol tartrate 50 mg

metoprolol tartrate 50 mg single oral dose

DRUG

Sildenafil25 mg

Sildenafil 25 mg single oral dose

Sponsors & Collaborators

  • Forest Laboratories

    collaborator INDUSTRY

  • Vanderbilt University

    lead OTHER

Principal Investigators

  • Italo Biaggioni, MD · Vanderbilt University

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2014-07-31
Completion
2014-08-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01044693 on ClinicalTrials.gov