Effects of Hookah Smoking on Blood Flow to the Heart, Muscle and Skin
NCT02147665 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42
Last updated 2020-01-13
Summary
This is a pilot study on acute effects of Hookah smoking on the sympathetic neural control of the human cardiovascular system. Hookah smoking is known to transiently increase blood pressure and heart rate while decreasing heart rate variability suggesting - but not proving - sympathetic mediation. Here the investigators will directly measure the acute effects of Hookah smoking on sympathetic nerve activity with microneurography (intraneural microelectrodes) and quantify associated regional changes in vasomotor tone.
Conditions
- Hookah Smoking
Interventions
- OTHER
-
Hookah smoking
Subjects will smoke waterpipe in a controlled research environment.
Sponsors & Collaborators
-
Cedars-Sinai Medical Center
lead OTHER
Principal Investigators
-
Ronald G Victor, MD · Cedars-Sinai Medical Center
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 39 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-03-31
- Primary Completion
- 2016-03-31
- Completion
- 2016-03-31
Countries
- United States
Study Locations
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