The Effect of Smoking on Thermoregulation
NCT01596556 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2014-05-09
Summary
To the best of our knowledge, a possible relation between smoking and heat injuries or heat intolerance was never scientifically examined, although such a relation is logical according to the observations that smoking has a thermogenic effect, decreases physical fitness and affects the body's heat dissipation.16 healthy young male volunteers will participate in the study, 8 smokers and 8 non-smokers. They will arrive to our lab four or six times. They will perform VO2 test and heat tolerance test (HTT) in different conditions.
Conditions
- Cigarette Smoking
Interventions
- DRUG
-
Nicotine
both groups will be given nicotine lozenges before a VO2 test and a HTT.
- OTHER
-
cigarette smoking
the smokers will smoke 2 cigarettes before a VO2 exam and a HTT.
Sponsors & Collaborators
-
International Diabetes Federation
collaborator OTHER -
Sheba Medical Center
lead OTHER_GOV
Principal Investigators
-
Amit Druyan, M.D · Sheba Medical Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-06-30
- Primary Completion
- 2013-12-31
- Completion
- 2014-05-31
Countries
- Israel
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