Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.

Summary

Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address the question - is a smoking cessation intervention personalized to high anxiety sensitive smokers and adapted for implementation by the YMCA effective among racially/ethnically diverse samples?

Conditions

• Nicotine Dependence

Interventions

BEHAVIORAL

Aerobic Exercise

Participants will select a YMCA branch and will be assigned a personal fitness instructor who will oversee a 15-week exercise intervention. The weekly exercise prescription is 75 minutes of aerobic training.

BEHAVIORAL

Counseling

Participants will receive the standard tobacco cessation package of up to 5 proactive interactions from the Texas Tobacco Quitline (TTQ). Interactions are typically phone calls, but can be chat or live text if the participant prefers. Interaction 1 is for assessment and quit date planning, Interaction 2 occurs prior to the quit date and can be a group session, Interaction 3 occurs shortly following the quit date, and Interactions 4 and 5 are for relapse prevention if the smoker has quit or problem solving if they have not quit. TTQ also offers a tobacco cessation text messaging program and access to a web portal with a variety of cessation resources.

DRUG

Nicotine patch

On the target quit day (week 6), participants will be provided 8 weeks of nicotine replacement therapy (24-hour transdermal nicotine patches \[TNP\]).

Sponsors & Collaborators

• University of Houston

  collaborator OTHER

• University of Oklahoma

  collaborator OTHER

• National Cancer Institute (NCI)

  collaborator NIH

• YMCA

  collaborator OTHER

• Jasper A. Smits

  lead OTHER

Principal Investigators

• Jasper Smits, PhD · University of Texas at Austin

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-12-27

Primary Completion

2029-03-31

Completion

2029-06-30

FDA Drug

Yes

Countries

• United States

Study Locations