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Gene Expression in the Overactive Bladder in Children

NCT02086058 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 46

Last updated 2015-12-18

No results posted yet for this study

Summary

The aim of this study (the hypothesis) is to identify differences in the gene expression profile in the bladder muscle and hereby gain greater knowledge about the muscular mechanisms that cause overactive bladder and daytime urinary incontinence in children older than 5 years. A secondary aim is to examine how this gene expression profile differs from children with a neurogenic overactive bladder and how the gene expression profile changes from childhood till adulthood. Such new knowledge will result in a more precisely targeted and hence effective treatment of overactive bladder.

The results will be obtained by retrieving bladder biopsies from children and adults suffering from an overactive bladder or a neurogenic bladder. These biopsies will undergo molecular analysis and the investigators will compare them with biopises from bladder healthy adults and children.

Conditions

Sponsors & Collaborators

  • University Hospital, Ghent

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Luise Borch, M.D · University of Aarhus

Eligibility

Min Age
5 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2016-09-30
Completion
2016-11-30

Countries

  • Denmark

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02086058 on ClinicalTrials.gov