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Pharmacology and Physiology of the Lower Urinary Tract

NCT00662064 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2008-06-20

No results posted yet for this study

Summary

The function of the lower urinary tract is simple - urine storage and voiding. However, despite this simplicity of function, the control of the lower urinary tract is a rather complex, multilevel process (urothelium, detrusor, peripheral nerves, spinal cord and higher cerebral centres) and the mechanisms involved remain poorly elucidated.

This study is designed to gain a more in depth understanding of the lower urinary tract function. Using bladder biopsies, tissue staining for characteristic markers present on nerves and other cells will be performed. We hypothesize that certain markers are altered in disease and turn back towards the control level of healthy people or patients with successful medical treatment.

Conditions

  • Urologic Diseases

Sponsors & Collaborators

  • University College London Hospitals

    lead OTHER

Principal Investigators

  • Clare J Fowler, FRCP · Department of Uro-Neurology, National Hospital for Neurology and Neurosurgery, University College London Hospitals, London, UK

  • Suzy Elneil, PhD, MRCOG · Department of Uro-Neurology, National Hospital for Neurology and Neurosurgery, University College London Hospitals, London, UK

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-02-28
Primary Completion
2008-12-31
Completion
2008-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00662064 on ClinicalTrials.gov