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Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children

NCT05989646 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 65

Last updated 2026-04-20

No results posted yet for this study

Summary

The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the aim is to investigate if sacral transcutaneous electric nerve stimulation (TENS) has a central mechanism of action. Children with OAB and DUI will be recruited from involved pediatric departments, and functional magnetic resonance imaging (fMRI) will be performed before and after 10 weeks of sacral TENS. In healthy children without bladder symptoms, only the baseline fMRI will be performed.

Conditions

  • Urinary Incontinence
  • Daytime Wetting
  • Urination Disorders
  • Urination Involuntary
  • Urologic Diseases
  • Lower Urinary Tract Symptoms
  • Urological Manifestations
  • Behavioral Symptoms
  • Mental Disorders
  • Elimination Disorders

Interventions

DEVICE

Sacral TENS

Sacral TENS applied two hours daily for 10 weeks

Sponsors & Collaborators

  • Aarhus University Hospital

    collaborator OTHER

  • Regional Hospital West Jutland

    collaborator OTHER

  • Regionshospital Nordjylland

    collaborator OTHER_GOV

  • Aalborg University Hospital

    lead OTHER

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
6 Years
Max Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-05-05
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05989646 on ClinicalTrials.gov