Observational Study of Dental Outcomes in Head and Neck Cancer Patients
NCT02057510 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 575
Last updated 2025-07-01
Summary
The purpose of this study is to measure the two-year rate of tooth loss in patients who have received external beam radiation therapy with curative intent for head and neck cancer. The study will also evaluate the sequelae of radiation therapy and oral complications that may occur as a result to receiving radiation therapy.
Conditions
- Head and Neck Cancer
- Dental Disease
- Xerostomia
- Osteoradionecrosis
Sponsors & Collaborators
-
National Institute of Dental and Craniofacial Research (NIDCR)
collaborator NIH - collaborator OTHER
-
UConn Health
collaborator OTHER - collaborator OTHER
-
Brigham and Women's Hospital
collaborator OTHER - collaborator OTHER
-
University of North Carolina
collaborator OTHER -
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
Michael T Brennan, DDS, MHS · Wake Forest University Health Sciences
-
Rajesh Lalla, DDS, PhD · University of Connecticut Health Center - School of Dental Medicine
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-02-28
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
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