The Expression of Aquaporin 3, 8 and 9 in Placenta in Normal and Preeclamptic Pregnancies: Perinatal and Neonatal Outcomes.
NCT02045316 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 210
Last updated 2014-01-24
Summary
The etiologic agent responsible for the development of preeclampsia remains unknown. Aquaporins, members of integral membrane proteins, are responsible of water molecules movements through the plasma membrane channels, energy metabolism and associated with changes in cellular volume during apoptosis.
İn such placental pathology as preeclampsia, characterized with superficial implantation and increased apoptosis leading to a relative hypoxia between mother and fetus, the hypothesis of aquaporins important role in energy homeostasis and apoptosis maybe suggested.
Conditions
Sponsors & Collaborators
-
Rakhshanda Aslanova
lead OTHER
Principal Investigators
-
Cenk Sayin, Professor · Trakya University
Eligibility
- Min Age
- 17 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-03-31
- Primary Completion
- 2014-06-30
- Completion
- 2014-07-31
Countries
- Turkey (Türkiye)
Study Locations
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