Expression of Angiogenic Factors in Myocardial Tissue

NCT01414621 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2016-03-08

No results posted yet for this study

Summary

The purpose of this study is to evaluate whether angiogenesis is decreased in diabetic patients with coronary artery disease compared to non-diabetics with coronary artery disease. The protein expression of angiogenic factors will be examined in atrial tissue prior to initiation of cardiopulmonary bypass in patients undergoing coronary bypass surgery.

The goal of this project is to evaluate the tissue levels of HIF-1, VEGF and angiostatin in diabetic and non-diabetic patients coming for on-pump coronary artery bypass graft (CABG).

Conditions

Interventions

OTHER

atrial tissue sample

atrial tissue sample from CABG patient

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Jacob Raphael, MD · UVA Anesthesiology

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2011-07-31
Completion
2011-08-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01414621 on ClinicalTrials.gov