Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide
NCT00250211 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2016-02-24
Summary
The purpose of this study is to learn whether 3 tesla (3T) MRI functional imaging will map a tumor more accurately allowing a more targeted delivery of radiation. The investigators hope to learn whether tomotherapy will be able to deliver higher radiation doses safely to the tumor while sparing the surrounding normal tissue.
Conditions
Interventions
- PROCEDURE
-
Functional MRI imaging and tomotherapy
Sponsors & Collaborators
-
Cross Cancer Institute
collaborator OTHER -
AHS Cancer Control Alberta
lead OTHER
Principal Investigators
-
Bassam Abdulkarim, MD · AHS Cancer Control Alberta
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-03-31
- Primary Completion
- 2011-03-31
- Completion
- 2011-04-30
Countries
- Canada
Study Locations
More Related Trials
-
Hypofractionated Radiotherapy
NCT06740955 ·Status: RECRUITING ·Phase: NA
-
Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors
NCT00659126 ·Status: TERMINATED ·Phase: PHASE2
-
Correlative Analysis Between Magnetic Resonance Spectroscopy (MRS) and Essential Clinicobiological Data in Glioblatoma Multiforme (GBM)
NCT07211841 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of the Capacity of the MRI Spectroscopy to Define the Tumor Area Enriched in Glioblastoma Stem Cells. Proof of Concept Study
NCT01872221 ·Status: COMPLETED ·Phase: NA
-
Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components
NCT00813787 ·Status: UNKNOWN
-
LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas
NCT05663125 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain Metastasis
NCT01705548 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Human Brain Tumor Therapy Response by Magnetic Resonance (MR)
NCT00724191 ·Status: COMPLETED
-
Radiomics for Prediction of Survival in GBM
NCT02666066 ·Status: COMPLETED
-
FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy
NCT03370926 ·Status: UNKNOWN
-
Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma
NCT04540107 ·Status: RECRUITING ·Phase: PHASE1
-
MR Perfusion Methods in Patients With Suspected Recurrent High Grade Gliomas
NCT02919865 ·Status: COMPLETED ·Phase: NA
-
Amino-acid PET Versus MRI Guided Re-irradiation in Patients With Recurrent Glioblastoma Multiforme
NCT01252459 ·Status: UNKNOWN ·Phase: PHASE2
-
Feasibility Study on LITT for Newly Diagnosed Glioblastoma
NCT02880410 ·Status: TERMINATED ·Phase: PHASE1
-
Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
NCT01227954 ·Status: COMPLETED ·Phase: PHASE2
-
Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study
NCT06002711 ·Status: RECRUITING
-
Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma
NCT02394665 ·Status: TERMINATED ·Phase: PHASE2
-
MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors
NCT00147056 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas
NCT00274755 ·Status: COMPLETED ·Phase: PHASE2
-
Magnetic Resonance Imaging in Evaluating Response to RadiationTherapy in Patients With High Grade Glioma
NCT01018329 ·Status: COMPLETED ·Phase: NA
-
Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction MRI
NCT06201351 ·Status: NOT_YET_RECRUITING
-
Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging
NCT03102203 ·Status: UNKNOWN
-
Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma
NCT02540135 ·Status: WITHDRAWN ·Phase: NA
-
PET (FDG)-MR Imaging for the Adult Patients Presented With Brain Tumor
NCT02071017 ·Status: UNKNOWN
-
Neurococognitive and Functioal Assessment of Patients With Brain Metastases
NCT01861405 ·Status: UNKNOWN