Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment
NCT05559853 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 119
Last updated 2026-03-06
Summary
The purpose of this study is to develop and test a new magnetic resonance imaging (MRI) technique to see if it can be used to tell the difference between tumor growth from worsening of cancer and growth from the effects of treatment in participants who have brain tumors treated with radiation therapy called stereotactic radiosurgery (SRS).
Conditions
- Brain Metastases
- Brain Metastases, Adult
- Metastatic Brain Tumor
- Metastatic Brain Cancer
Interventions
- DIAGNOSTIC_TEST
-
CEST-MRF
CEST-MRF enables accurate quantification of both proton exchange rates and volume fractions in a fraction of the time required by conventional pulse sequences will be developed and optimized.
Sponsors & Collaborators
-
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Ouri Cohen, PhD · Memorial Sloan Kettering Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-09-22
- Primary Completion
- 2027-09-22
- Completion
- 2027-09-22
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Radiomics for Prediction of Long Term Survival and Local Failure After Stereotactic Radiotherapy for Brain Metastases
NCT02265549 ·Status: COMPLETED
-
Preop fSRS for Resectable Brain Metastases
NCT05267587 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
NCT05692635 ·Status: RECRUITING ·Phase: PHASE2
-
MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases
NCT04246879 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
High Resolution Magnetic Resonance Imaging in Patients With Brain Tumors
NCT02035852 ·Status: COMPLETED
-
Evaluation of Human Brain Tumor Therapy Response by Magnetic Resonance (MR)
NCT00724191 ·Status: COMPLETED
-
Magnetic Resonance Imaging in Determining Extent of Cancer in Patients With Newly Diagnosed Glioma
NCT00005082 ·Status: COMPLETED ·Phase: NA
-
Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
NCT06455189 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Advanced MRI Applications Development
NCT01847833 ·Status: UNKNOWN
-
Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
NCT00870129 ·Status: RECRUITING ·Phase: NA
-
CEST in Low-grade Glioma Study
NCT05996653 ·Status: RECRUITING ·Phase: NA
-
Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors
NCT00581906 ·Status: ACTIVE_NOT_RECRUITING
-
Stereotactic Radiosurgery (SRS) for Multiple CNS Mets
NCT02567643 ·Status: WITHDRAWN ·Phase: NA
-
Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases
NCT03698162 ·Status: TERMINATED ·Phase: NA
-
Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors
NCT00659126 ·Status: TERMINATED ·Phase: PHASE2
-
ioMRI in the Surgery of Brain Metastases.
NCT07197632 ·Status: RECRUITING ·Phase: NA
-
Image-Guided Stereotactic Biopsy of High Grade Gliomas
NCT00979810 ·Status: COMPLETED ·Phase: NA
-
MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma
NCT00756106 ·Status: TERMINATED ·Phase: NA
-
A Neurocognitive Study in Patients With Brain Oligometastases Receiving Hypofractionated SRT
NCT04805255 ·Status: RECRUITING
-
Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain Metastasis
NCT01705548 ·Status: COMPLETED ·Phase: NA
-
New MRI Biomarkers in Head and Neck Cancers
NCT03483337 ·Status: RECRUITING
-
Neurococognitive and Functioal Assessment of Patients With Brain Metastases
NCT01861405 ·Status: UNKNOWN
-
Magnetic Resonance Imaging-guided Adaptive Radiotherapy for Large Brain Metastases
NCT06405256 ·Status: RECRUITING
-
PET (FDG)-MR Imaging for the Adult Patients Presented With Brain Tumor
NCT02071017 ·Status: UNKNOWN
-
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas
NCT00274755 ·Status: COMPLETED ·Phase: PHASE2