The Influence of Autophagy on Fatty Liver
NCT01988441 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 800
Last updated 2023-09-14
Summary
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. It is not known why only some obese subjects develop NAFLD. In recent years, a growing body of evidence showed a crucial role of autophagy in in the regulation of liver fat storage. The purpose of this study is to determine whether autophagy pathway-related genetic polymorphisms affect NAFLD.
Conditions
- Non-alcoholic Fatty Liver Disease
- Obesity
Sponsors & Collaborators
-
Ministry of Science and Technology, Taiwan
collaborator OTHER_GOV -
Far Eastern Memorial Hospital
lead OTHER
Principal Investigators
-
Yu-Cheng Lin, M.D., Ph.D. · Far Eastern Memorial Hospital
Eligibility
- Min Age
- 6 Years
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-09-30
- Primary Completion
- 2025-08-31
- Completion
- 2025-08-31
Countries
- Taiwan
Study Locations
More Related Trials
-
Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease
NCT07265544 ·Status: RECRUITING
-
Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure
NCT03598465 ·Status: COMPLETED
-
Quantitative Diagnosis of Fatty Liver by Dual Energy CT Technique
NCT00172705 ·Status: UNKNOWN
-
Mechanisms of Macrophage Polarization in HIRI in Patients With NAFLD
NCT06950710 ·Status: ACTIVE_NOT_RECRUITING
-
Clinical Application of Non-invasive Assessment for Staging Liver Steatosis and Liver Fibrosis
NCT03386890 ·Status: UNKNOWN
-
Impact of Muscle Insulin Resistance on the Pathogenesis of Non Alcoholic Steatohepatitis
NCT01324414 ·Status: COMPLETED
-
Fatty Acids, Genes and Microbiota in Fatty Liver
NCT02148471 ·Status: COMPLETED
-
Macrophage-mediated Inflammation in White Adipose Tissue and Non-alcoholic Fatty Liver Disease.
NCT04059068 ·Status: COMPLETED
-
Liver Fibrosis in Peri-menopausal Women
NCT03602573 ·Status: UNKNOWN
-
Dynamic Changes and Risk Factors of Fibrosis and Steatosis Progression in Nonalcoholic Fatty Liver Disease
NCT03635541 ·Status: UNKNOWN
-
Fatty Liver and Ectopic Fat in Overweight and Obese Patients
NCT00886301 ·Status: COMPLETED ·Phase: NA
-
Monitoring Changes in Hepatic Steatosis Using Continuous Controlled Attenuation Parameter
NCT06203548 ·Status: RECRUITING ·Phase: NA
-
Simultaneous Quantification of Liver Fat Content, Fatty Acid Composition, and Fibrosis Using Spin-lock MRI for Steatohepatitis Assessment
NCT05384652 ·Status: ACTIVE_NOT_RECRUITING
-
Identification of Protective and Worsening Steatohepatitis (NASH) Factors
NCT00914446 ·Status: UNKNOWN ·Phase: NA
-
Liver Regeneration After Liver Resection
NCT01220986 ·Status: UNKNOWN
-
Precise Evaluation Criteria for Histological Regression of NASH Fibrosis
NCT06364462 ·Status: NOT_YET_RECRUITING
-
Systemic Inflammation in Liver Cirrhosis
NCT04850534 ·Status: COMPLETED
-
Evaluation of Multi-Organ Metabolism and Perfusion in NAFLD by Total Body Dynamic PET Scan on EXPLORER
NCT04165343 ·Status: COMPLETED
-
Non-invasive Diagnostic Model of Liver Fibrosis Associated With NAFLD and Prediction of Prognosis
NCT03842748 ·Status: UNKNOWN
-
Non Alcoholic Fatty Liver Disease (NAFLD) in Hong Kong
NCT00577044 ·Status: UNKNOWN
-
Dissection of the Molecular and Immunological Interaction in Patients With HCC of Viral and Non-viral Etiologies
NCT05613621 ·Status: ACTIVE_NOT_RECRUITING
-
Longitudinal Study of Mitochondrial Hepatopathies
NCT01148550 ·Status: SUSPENDED
-
Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) Utilizing Ultrasound and Percutaneous Liver Biopsy
NCT01100398 ·Status: COMPLETED
-
Oxidative Stress and Fatty Acids in Hepatitis C
NCT00444002 ·Status: COMPLETED
-
Clinical, Biochemical and Body Composition Analysis in Assessment of Steatosis in Non Alcoholic Fatty Liver Disease
NCT04946786 ·Status: UNKNOWN