MedTrace Logo

Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome

NCT00810329 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 160

Last updated 2014-02-25

No results posted yet for this study

Summary

The purpose of this study is:

1. To identify specific set of proteins in the cerebrospinal fluid (fluid surrounding the brain and the spinal cord), that are believed to be seen in Chronic fatigue syndrome (CFS) patients, but not in healthy controls (HC). A similar study that the investigators had conducted before,suggested that significant changes in proteins in the cerebrospinal fluid may be due to the fundamental pathology of this disorder.
2. Increased cerebrospinal fluid pressure (pressure that helps the cerebrospinal fluid to move around the brain and the spinal cord), may be related with certain symptoms like headache, sleep problems, light headedness, increased pain, excessive tiredness (fatigue) even with minimal work and memory problems.
3. Assessment of Autonomic Nervous system function (Sympathetic nervous system)between the CFS and HC.
4. Perform Lung Function Testing or pulmonary function test to estimate the lung capacities and score shortness of breath while performing breathing maneuvers.
5. Dolorimetry (18 tender point test) for assessment of pain threshold.
6. Capsaicin skin test
7. Allergy skin test

Conditions

  • Chronic Fatigue Syndrome
  • Fibromyalgia
  • Gulf War Illness
  • Multiple Chemical Sensitivity
  • Interstitial Cystitis
  • Irritable Bowel Syndrome

Sponsors & Collaborators

  • National Institute of Environmental Health Sciences (NIEHS)

    collaborator NIH

  • University of South Alabama

    collaborator OTHER

  • Georgetown University

    lead OTHER

Principal Investigators

  • James N Baraniuk, MD · Georgetown University Hospital

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2011-04-30
Completion
2011-04-30

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00810329 on ClinicalTrials.gov