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Weaning From Mechanical Ventilation Guided by Lung Ultrasound (Brazilian WEANLUS)

NCT01966861 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2018-03-02

No results posted yet for this study

Summary

The present study aims to evaluate the impact of a weaning strategy based on identification of early signs of respiratory distress by lung ultrasound and the consequent implementation of a "clinical optimization" protocol as compared to usual care.

Conditions

  • Acute Respiratory Failure

Interventions

OTHER

weaning guided by LUS (lung ultrasound)

Predictive early signs of respiratory distress are assessed by lung ultrasound (LUS score \>14) and if present will trigger protocolised intervention (eg- fluid balance,diuretics, thoracocentesis, antibiotics when required \[CPIS\>6\], hemglobin\>8g/dl triggers transfusion)

Sponsors & Collaborators

  • Hospital Sirio-Libanes

    collaborator OTHER

  • University of Sao Paulo

    collaborator OTHER

  • Hospital Israelita Albert Einstein

    collaborator OTHER

  • D'Or Institute for Research and Education

    lead OTHER

Principal Investigators

  • Jorge IF Salluh, MD, PhD · D'Or Institute for Research and Education

  • Luiz M Malbouisson, MD, PhD · University of Sao Paulo

  • Fabiola Prior, MD · University of Sao Paulo

  • Julio Neves, MD · Hospital da Bahia

  • Jean-Jacques Rouby, MD · Paris University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2018-12-31
Completion
2019-05-31

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01966861 on ClinicalTrials.gov