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Community-Onset Bacteremia Due to ESBL Producing E.Coli or K.Pneumoniae in China: Prevalence, Risk Factors and Prognosis

NCT01961206 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 960

Last updated 2015-11-23

No results posted yet for this study

Summary

Escherichia coli is the leading cause of community-onset gram-negative bloodstream infections. There has been a dramatic increase in the prevalence of extended-spectrum b-lactamases producing E. coli and K.pneumoniae in the community, which was considered to be exclusively a nosocomial pathogen in recent years. As a result, the treatment options for community-onset infections due to ESBL-producing E. coli or K.pneumoniae are limited and the initial empirical therapy is often ineffective and associated with increased mortality. Although there were some reports of the risk factors of community-onset ESBL producing E. coli in Spain, Korea, and Canada, few empirical data were available about China. Therefore, the investigators aim was to investigate the epidemiology, risk factors, and the hospital outcomes for patients with community-onset bacteremia caused by ESBL producing E. coli or K.pneumoniae in China.

Conditions

  • Community Acquired Infection

Interventions

OTHER

bacteremia caused by ESBL producing E.coli or K.pneumoniae

community-onset bacteremia caused by ESBL producing E.coli or K.pneumoniae

Sponsors & Collaborators

  • Jian-cang Zhou M.D.

    lead OTHER

Principal Investigators

  • Yun-song YU, M.D · Sir Run Run Shaw Hospital

Eligibility

Min Age
18 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2014-11-30
Completion
2015-09-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01961206 on ClinicalTrials.gov