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Infections Caused by ESbL-Producing Enterobacteriaceae in Italy

NCT00404625 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 813

Last updated 2006-11-29

No results posted yet for this study

Summary

To assess the molecular epidemiology, clinical impact, treatment outcome and risk factors for infections caused by Enterobacteriaceae producing ESBLs in Italy in a large multicenter observational survey.

SPECIFIC OBJECTIVES

1. To collect consecutive nonreplicate isolates of Enterobacteriaceae resistant to expanded-spectrum cephalosporins from clinical specimens from inpatients and outpatients.
2. To characterize the isolates for resistance phenotypes and for β-lactam resistance mechanisms.
3. To investigate the clonality of isolates.
4. To analyse the epidemiology of various resistance mechanisms/resistant clones.
5. To collect clinical and epidemiological data for patients with infections caused by the ESBL producers.
6. To analyse the epidemiology, risk factors and outcome for infections caused by ESBL producers.

Conditions

Interventions

BEHAVIORAL

Risk factors for infections due to ESBL+ Enterobacteriaceae

BEHAVIORAL

Risk factors for inadequate initial antimicrobial therapy

BEHAVIORAL

Overall and 30-day mortality in bad first antibiotic therapy

Sponsors & Collaborators

Principal Investigators

  • Gian Maria Rossolini, professore · Università di Siena

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-10-31
Completion
2006-11-30

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00404625 on ClinicalTrials.gov