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Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units

NCT01948635 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 326

Last updated 2025-12-22

No results posted yet for this study

Summary

The investigators hypothesized that PVC tapered-cuff tracheal tubes would reduce microaspiration of gastric content as determined by pepsin level in tracheal aspirate.

Conditions

  • Critical Illness
  • Mechanical Ventilation Complication
  • Ventilator Associated Pneumonia

Interventions

DEVICE

tapered PVC-cuffed tracheal tubes

Patients will be intubated with tapered-shape tracheal tubes

DEVICE

Standard PVC-cuffed tracheal tube

Patients will be intubated with standard PVC cuffed tracheal tubes

Sponsors & Collaborators

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Saad Nseir, MD, PhD · CHRU de Lille

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2015-08-31
Completion
2015-08-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01948635 on ClinicalTrials.gov