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Continuous Control of Tracheal Cuff Pressure and Microaspiration in Critically Ill Patients

NCT01082666 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 122

Last updated 2026-04-22

No results posted yet for this study

Summary

We hypothesized that continuous control of tracheal cuff pressure would reduce microaspiration of gastric content as determined by pepsin level in tracheal aspirate.

Conditions

  • Critically Ill

Interventions

DEVICE

Continuous control of cuff pressure

Continuous control of cuff pressure using a pneumatic device (Nosten, Leved, France)

DEVICE

Manual control of cuff pressure

Manual control of cuff pressure is a routine practice in ICU patients

Sponsors & Collaborators

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Alain Durocher, MD · CHRU de Lille

  • Malika Balduyck, MD · CHU de Lille

  • Farid Zerimech, MD · CHU de Lille

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-10-31
Primary Completion
2010-08-31
Completion
2010-12-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01082666 on ClinicalTrials.gov