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Role of Intestinal Inflammation in the Pathogenesis of Type 1 Diabetes

NCT01940835 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27

Last updated 2022-02-02

No results posted yet for this study

Summary

This purpose of this study is to determine if activation of a person's immune system in the small intestine could be a contributing cause of Type 1 Diabetes.

Conditions

Interventions

PROCEDURE

Upper endoscopy with small bowel biopsies and brushings.

OTHER

Blood draw

Blood will be collected for serum, DNA, and peripheral blood mononuclear cells (PBMC).

OTHER

Stool sample

Stool samples will be collected at baseline for future microbiome and virome studies.

Sponsors & Collaborators

  • Juvenile Diabetes Research Foundation

    collaborator OTHER

  • University of Chicago

    collaborator OTHER

  • Harvard University

    collaborator OTHER

  • Mayo Clinic

    lead OTHER

Principal Investigators

  • Joseph Murray, M.D. · Mayo Clinic

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-09-30
Primary Completion
2019-06-19
Completion
2019-06-19

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01940835 on ClinicalTrials.gov