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Study of the Relationship Between Glycogen Storage Disease Type Ia and Inflammatory Bowel Disease

NCT01854242 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2020-07-28

Study results available
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Summary

The purpose of this research study is to understand the relationship between inflammatory bowel disease (IBD) and Glycogen storage disease (GSD)type Ia. GSD type Ib has been established to have an association with IBD with clinical and histologic features that mirror those of Crohn disease. Development of the disease seems to be related to the defect of neutrophil function in individuals with GSD type Ib and subsequent colonic inflammation. In the last decade, it has become a standard for patients with GSD type Ib and gastrointestinal symptoms to be evaluated for IBD. Patients with GSD type Ia were not recognized to have similar gastrointestinal symptoms until recently. The prevalence of IBD is greater in patients with GSD type Ia versus the general population.

Conditions

Interventions

OTHER

Glycogen Storage Disease type Ia patients

The participants will have one blood draw for this study. The test will be performed on the blood.

Sponsors & Collaborators

  • Prometheus Laboratories

    collaborator INDUSTRY

  • University of Florida

    lead OTHER

Principal Investigators

  • Nicole T Lawrence, MD · University of Florida

  • David A Weinstein, MD · University of Florida

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2014-10-31
Completion
2014-10-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01854242 on ClinicalTrials.gov