Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia

Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)

NCT01841684 ·Status: TERMINATED ·Phase: PHASE3

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

NCT01556906 ·Status: COMPLETED ·Phase: PHASE2

Functional and Clinical Impact of CYP3A Genetic Polymorphisms on Statin Therapy

NCT01867203 ·Status: WITHDRAWN

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

NCT03135184 ·Status: UNKNOWN ·Phase: NA

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

NCT00385658 ·Status: COMPLETED ·Phase: PHASE4

A Study of MK0859 in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia (MK-0859-011)(COMPLETED)

NCT00565292 ·Status: COMPLETED ·Phase: PHASE1

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.

NCT05425745 ·Status: COMPLETED ·Phase: PHASE3

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

NCT02722408 ·Status: COMPLETED ·Phase: PHASE2

Study in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

NCT03156621 ·Status: COMPLETED ·Phase: PHASE3

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

NCT01524289 ·Status: COMPLETED ·Phase: PHASE3

Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertension

NCT02178098 ·Status: COMPLETED ·Phase: PHASE2

Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)

NCT00726856 ·Status: COMPLETED

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022)

NCT01860729 ·Status: COMPLETED ·Phase: PHASE3

Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemia

NCT00136799 ·Status: COMPLETED ·Phase: PHASE3

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

NCT00730236 ·Status: COMPLETED ·Phase: PHASE3

Evaluate the Long-term Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

NCT07133815 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2

Genetic Influence on Statin Pharmacodynamics

NCT01569854 ·Status: WITHDRAWN

A Study of PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

NCT04173793 ·Status: COMPLETED ·Phase: PHASE2

Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy

NCT02765841 ·Status: WITHDRAWN ·Phase: PHASE3

Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Subjects With A Genetic Cholesterol Disorder.

NCT00145431 ·Status: TERMINATED ·Phase: PHASE3

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

NCT05217667 ·Status: TERMINATED ·Phase: PHASE2

Efficacy/Safety of HCP1306 Tablet Versus HGP0816 Tablet in Patients With Primary Hypercholesterolemia

NCT02205606 ·Status: COMPLETED ·Phase: PHASE3

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

NCT01350960 ·Status: TERMINATED ·Phase: PHASE1

GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol

NCT00158899 ·Status: COMPLETED ·Phase: PHASE2

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins

NCT06262685 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4