Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia
NCT01887587 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2020-01-22
Summary
This is a phase I study of vincristine, doxorubicin and dexamethasone (modified VXD) plus MLN9708 in adults with relapsed or refractory acute lymphoblastic leukemia/lymphoma, lymphoblastic lymphoma or mixed phenotype acute leukemia.
Conditions
- Relapsed or Refractory Acute Lymphoblastic Leukemia
- Relapsed or Refractory Lymphoblastic Lymphoma
- Mixed Phenotype Acute Leukemia
Interventions
- DRUG
-
MLN9708
- DRUG
-
Vincristine
- DRUG
-
Doxorubicin
- DRUG
Sponsors & Collaborators
-
Ehab L Atallah
lead OTHER
Principal Investigators
-
Ehab L Atallah, MD · Medical College of Wisconsin
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-06-30
- Primary Completion
- 2016-02-29
- Completion
- 2016-02-29
Countries
- United States
Study Locations
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