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Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?

NCT01870544 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2016-02-10

No results posted yet for this study

Summary

The purpose of the weight-loss study is to characterize the effect of LGG supplementation on the relative abundance of phyla in the gut microbiota of patients undergoing gastric bypass and sleeve gastrectomy surgery, and to elucidate a relationship between the gut microbiota pattern and the degree of weight-loss post-surgery.

The investigators hypothesize that LGG administration will result in a "leaner" pattern of gut microbiota that will lead to higher weight loss at 3 months post-surgery.

Conditions

Interventions

DIETARY_SUPPLEMENT

Lactobacillus Rhamnosus GG

LGG will be administered orally for 44 days

DIETARY_SUPPLEMENT

Placebo

placebo will be administered daily for 44 days

Sponsors & Collaborators

  • Tufts Medical Center

    lead OTHER

Principal Investigators

  • Shira Doron, MD · Tufts Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-09-30
Primary Completion
2016-01-31
Completion
2016-01-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01870544 on ClinicalTrials.gov