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Low-calorie Diet and Body Composition Prior to Roux-en-Y Gastric Bypass

NCT02144597 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2021-03-18

Study results available
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Summary

Losing weight before undergoing Roux-en-Y gastric bypass (RYGB) surgery may reduce liver fat content and size thereby improving surgical outcomes. This study aims to investigate whether a 2-week or 6-week pre-operative liquid formula low-calorie diet (LCD) reduces liver fat further than a conventional food diet prior to RYGB using magnetic resonance imaging (MRI). The hypothesis is that the 2-week and 6-week liquid formula LCD will reduce liver fat further than the conventional food pre-operative diet.

Conditions

  • Morbid Obesity
  • Liver Fat

Interventions

DIETARY_SUPPLEMENT

Liquid formula low-calorie diet (LCD)

The liquid formula low-calorie diet (LCD) will provide 800kcal/day from powdered milkshakes and soups. The diet will be provided by Cambridge Weight Plan.

PROCEDURE

Roux-en-Y gastric bypass (RYGB)

Participant went through Roux-en-Y gastric bypass (RYGB) surgery

OTHER

Control diet

Sponsors & Collaborators

  • Cambridge Weight Plan Limited

    collaborator INDUSTRY

  • Imperial College London

    lead OTHER

Principal Investigators

  • Prof Gary S Frost, RD PhD · Imperial College London

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2014-04-30
Completion
2014-04-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02144597 on ClinicalTrials.gov