Prognostic Value of Aβ Imaging in NPH Prior to Shunt Placement
NCT01834625 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 2
Last updated 2022-02-01
Summary
In this pilot study the investigators shall prospectively in a blinded fashion evaluate with Aβ PET in patients committed to shunt surgery and then investigate the relationship of these biomarkers with outcome on gait, cognition and urinary control improvement in the short term (3 months) and long term (1 year). The imaging agent will be provided by AVID.
Furthermore the study will standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden.
Conditions
- Normal Pressure Hydrocephalus Patients
Interventions
- DIAGNOSTIC_TEST
-
PET scan
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Neill R Graff-Radford, MD · Mayo Clinic
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-04-30
- Primary Completion
- 2017-03-31
- Completion
- 2017-10-31
Countries
- United States
Study Locations
More Related Trials
-
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral Beta-Amyloid When Compared With Postmortem Histopathology
NCT01886820 ·Status: UNKNOWN ·Phase: PHASE3
-
PET-MRI Imaging in Patients With Acute Neurovascular Syndrome
NCT03215563 ·Status: COMPLETED
-
Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Clinical Practice
NCT03232463 ·Status: ENROLLING_BY_INVITATION
-
Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging
NCT04436068 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation
NCT02811744 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy and Safety of the PET Imaging Agent [18F]NAV4694 in Subjects With Probable Alzheimer's Disease
NCT01680588 ·Status: UNKNOWN ·Phase: PHASE2
-
Value of MRI CSF Flowmetry in Assessment of Grey Zone Hydrocephalic Patients
NCT04060810 ·Status: UNKNOWN ·Phase: NA
-
Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral Hemorrhage
NCT05499169 ·Status: TERMINATED
-
PET Tau - Neurodegenerative Disease Imaging
NCT03143374 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
MRI Repository for Acute Stroke Clinical and Research Applications
NCT04144530 ·Status: WITHDRAWN
-
Assessing Brain Injury Using Portable Magnetic Resonance Imaging (MRI)
NCT05469139 ·Status: COMPLETED
-
[18F]PI-2620 Phase 3 Histopathological Study
NCT05641688 ·Status: RECRUITING ·Phase: PHASE3
-
Diagnostic Utility of MRI in Intracerebral Hemorrhage
NCT00363662 ·Status: COMPLETED
-
Cohort Study on the Effects of Aging in Acquired Brain Injury Patients
NCT05499806 ·Status: UNKNOWN
-
PET-MRI Imaging in Patients With Symptomatic Carotid Artery Stenosis
NCT03215550 ·Status: COMPLETED
-
PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers
NCT01826110 ·Status: COMPLETED ·Phase: PHASE1
-
Estimating Brain Biomechanics Using MRI
NCT01633268 ·Status: COMPLETED
-
The Value of Advanced Imaging Sequences for Fetal MRI in Clinical Practice
NCT03302663 ·Status: RECRUITING ·Phase: NA
-
A Trial of 18F-AV-133 and 18F-AV-45 Positron Emission Tomography (PET)
NCT01503944 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy
NCT05242666 ·Status: UNKNOWN ·Phase: NA
-
Stepped-Wedge Cluster Randomized Trial of AI-Assisted CTA Detection for Intracranial Aneurysms in Regional Hospitals
NCT07124624 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Pilot Study of the Use of a Portable Cranial Scanner in Intensive Care for Cerebro-injured Patients
NCT05891522 ·Status: COMPLETED ·Phase: NA
-
Research on Acetabular Labrum Injury Based on MR: Multi-angle Deep Learning Model
NCT04950036 ·Status: COMPLETED
-
Positron Emission Tomography of Amyloid in Alzheimer's Disease
NCT00205621 ·Status: SUSPENDED ·Phase: PHASE1
-
68Ga-NY104 PET/CT in Von Hippel-Lindau Disease
NCT05810246 ·Status: RECRUITING ·Phase: PHASE2