PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers
NCT01826110 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 21
Last updated 2019-03-05
Summary
The purpose of this study is to investigate the radiotracer \[11C\] PIB in participants with probably Alzheimer's Disease (AD) and healthy age-matched controls.
Conditions
Interventions
- DRUG
-
[11C]PIB
Approximately 15 mCI \[11C\]PIB IV x1
Sponsors & Collaborators
-
National Institute on Aging (NIA)
collaborator NIH - lead OTHER
Principal Investigators
-
Dean F Wong, MD, PhD · Johns Hopkins University
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-09-30
- Primary Completion
- 2018-07-31
- Completion
- 2018-07-31
Countries
- United States
Study Locations
More Related Trials
-
Neuroinflammation Imaging in AD
NCT04274998 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Imaging of Brain Amyloid Plaques in the Aging Population
NCT00950430 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE4
-
A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects
NCT01992380 ·Status: COMPLETED ·Phase: PHASE1
-
18F-AV-1451 Autopsy Study
NCT02516046 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of [18F] PBR111 and PET as a Marker of Inflammation in Subjects With Neurological Conditions
NCT01209156 ·Status: COMPLETED ·Phase: PHASE1
-
Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07
NCT01447719 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial of 18F-AV-133 and 18F-AV-45 Positron Emission Tomography (PET)
NCT01503944 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
FluoroAv45 Imaging Research-in Alzheimer's Disease
NCT01325259 ·Status: COMPLETED ·Phase: PHASE2
-
Positron Emission Tomography (PET) Study in Patients With Alzheimer's Disease
NCT03307993 ·Status: TERMINATED ·Phase: PHASE1
-
Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers
NCT01009359 ·Status: COMPLETED ·Phase: PHASE1
-
11C-PIB PET Study in MESA at Columbia University
NCT03981380 ·Status: COMPLETED
-
Can the Assessment of the Subhippocampal Region Contribute to the Detection of Early Diagnosis of Alzheimer's Disease? A Validation Study Using PET With Florbetapir (AV-45).
NCT01746706 ·Status: UNKNOWN ·Phase: NA
-
[18F]PI-2620 Phase 3 Histopathological Study
NCT05641688 ·Status: RECRUITING ·Phase: PHASE3
-
Biodistribution, Pharmacokinetics, and Safety of F-18 THK-5351 PET in Alzheimer's Disease Patients and Healthy Subjects.(Positron Emission Tomograph )
NCT02686216 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Positron Emission Tomography (PET) Imaging With MNI-558
NCT01217021 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
PET Study With 11 C-PIB to Evaluate Amyloid Protein Deposits in Mild Cognitive Disorder, Alzheimer's Disease and Early Frontotemporal Degeneration.
NCT06179979 ·Status: COMPLETED
-
A Non-drug Methods Study in Participants With Alzheimer's Disease
NCT01459016 ·Status: COMPLETED ·Phase: PHASE1
-
First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
NCT05374278 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
[18F]ACI-19626 PET in TDP-43 Proteinopathies
NCT06891716 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Positron Emission Tomography (PET) Study With [11C]AZD2995 and [11C]AZD2184, Candidate PET Ligands for β Amyloid
NCT00692705 ·Status: COMPLETED ·Phase: PHASE1
-
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
NCT03503331 ·Status: RECRUITING ·Phase: PHASE2
-
Assess Fibrin in Brains With AD/ADRD
NCT05336695 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Tau Imaging in Young Onset Dementia
NCT02289118 ·Status: COMPLETED
-
Influence of Age on Amyloid Load in Alzheimer's Disease and in Atypical Focal Cortical Alzheimer's Disease
NCT01095744 ·Status: COMPLETED
-
PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]Rolipram
NCT00250172 ·Status: COMPLETED ·Phase: PHASE1