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The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed Patients

NCT01785355 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2019-07-23

No results posted yet for this study

Summary

Several studies revealed a direct relationship between the severity of periodontal inflammation and CRP (NHANES III, Dumitriu HT et al, 1998). In patients without any other source of inflammation but PDD, proper dental treatment of the disease decreased CRP to normal levels (Dumitriu H.T. et al., 1998; D'Aiuto F. et al, 2004; Borawski J. et al., 2007) Moreover, a direct link between high levels of CRP and atherosclerotic complications has been found in studies conducted both in general population (Ridker PM, et al., 1998; Koenig W, et al., 1999) and in HD subjects (Westhuyzen J, et al., 2000; Iseki K., et al., 1999; Zimmermann J, et al. 1998).

Conditions

Interventions

OTHER

Dental treatment

1. The preliminary stage deals with: * assessment of the clinical state of the patient by completing a detailed dental and periodontal chart * education of the patient regarding correct oral hygiene habits; 2. Phase I Therapy: * plaque control : removal of dental plaque, calculus and root planning; antimicrobial therapy (local or systemic) * evaluation of response to the treatment 3. Phase II Therapy - surgical phase: * extraction of hopeless teeth * evaluation of the surgical results. 4. Maintenance phase: * periodic reevaluation of plaque and calculus and of periodontal conditions.

Sponsors & Collaborators

  • Anemia Working Group Romania

    lead OTHER

Principal Investigators

  • Oana Slusanschi, DMD · University of Medicine and Pharmacy Bucharest

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2021-09-30
Completion
2022-06-30

Countries

  • Romania

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01785355 on ClinicalTrials.gov