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Effect of Non-surgical Periodontal Treatment and C-reactive Protein Levels in Hemodialysis Patients

NCT04262011 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 88

Last updated 2020-02-20

No results posted yet for this study

Summary

The presence of periodontitis has been hypothesized as a risk factor for several systemic outcomes, including chronic kidney disease (CKD). Therefore, the aim of this study is to evaluate the impact of non-surgical periodontal treatment on CRP levels and quality of life of patients with chronic kidney disease undergoing hemodialysis (HD) in Santa Maria-RS.

Conditions

  • Chronic Kidney Disease Stage 5
  • Periodontitis

Interventions

PROCEDURE

immediate treatment

Patients allocated to the immediate treatment group will receive full mouth treatment, and will use 0.12% chlorhexidine mouthwash, every 12 hours for a week, and will receive oral hygiene instructions throughout the follow-up period. Patients will be evaluated at the beginning, at 3 and 6 months.

PROCEDURE

postponed treatment

Patients allocated to the late treatment group will be assessed at baseline, 3 and 6 months. After the end of the follow-up period, they will receive non-surgical periodontal treatment performed in four sessions.

Sponsors & Collaborators

  • Universidade Federal de Santa Maria

    lead OTHER

Principal Investigators

  • Raquel P Antoniazzi, pHD · Universidade Federal de Santa Maria

  • Samantha S Santi, DS · Universidade Federal de Santa Maria

  • Leandro M Oliveira, MS · Universidade Federal de Santa Maria

  • Rafaela V Palmeira, MS · Universidade Federal de Santa Maria

  • Catiusse C Del'Agnese, MS · Universidade Federal de Santa Maria

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-29
Primary Completion
2020-11-01
Completion
2021-06-01

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04262011 on ClinicalTrials.gov