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Myocardial Involvement in Carriers of Duchenne Muscular Dystrophy: An MRI-study

NCT01712152 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2016-10-04

No results posted yet for this study

Summary

Carriers of Duchenne muscular dystrophy (DMD) often have no severe symptoms of the scelet muscles, but they may develop a poor heart function due to the involvement of the heart muscle. Ultrasound of the heart is recommended, but it can detect a cardiac affection only after the heart has already become weaker. Cardiac magnetic resonance tomography can detect myocardial fibrosis already at preserved heart function and may facilitate early therapy. In our study, diagnosed carriers of DMD will undergo examinations of the heart by blood tests, EKG, heart ultrasound and magnetic resonance at enrollment and after one year in order to assess the extent of cardiac affection and its association with the clinical development.

Conditions

  • Carrier of Duchenne Muscular Dystrophy

Sponsors & Collaborators

  • Oesterreichische Muskelforschung

    collaborator UNKNOWN

  • Hospital Rudolfstiftung

    lead OTHER

Principal Investigators

  • Paul Wexberg, MD · Hospital Rudolfstiftung

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2014-04-30
Completion
2015-09-30

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01712152 on ClinicalTrials.gov