A Comparison of microRNA Samples in Patients With Nasal Polyps and Aspirin Exacerbated Respiratory Disease and Those With Nasal Polyps Only
NCT01631773 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26
Last updated 2014-10-07
Summary
We hypothesize that the miRNA expression in subjects with nasal polyps and Aspirin-exacerbated respiratory disease (AERD) differs from the miRNA expressed in subjects with nasal polyps but without Aspirin-exacerbated respiratory disease (AERD).
Conditions
- Aspirin-exacerbated Respiratory Disease
- Nasal Polyp
Interventions
- GENETIC
-
microRNA
Biological samples will be taken from subjects w/ Nasal polyps \& AERD disease and subjects w/ nasal polyps without AERD. MicroRNA will be analyzed to compare genetic similarities and differences between the two study groups.
Sponsors & Collaborators
-
University of South Florida
lead OTHER
Principal Investigators
-
Dennis Ledford, MD · Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida College of Medicine
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-08-31
- Primary Completion
- 2012-06-30
- Completion
- 2012-06-30
Countries
- United States
Study Locations
More Related Trials
-
Characterisation of the Nasal Microbiome in Patients With N-ERD
NCT04375293 ·Status: COMPLETED ·Phase: NA
-
A Study in Male and Female Adult Participants With Chronic Rhinosinusitis With Nasal Polyps In the Greater Gulf Region
NCT05649813 ·Status: COMPLETED
-
The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory Phenotype
NCT04171167 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease
NCT05575037 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
The Factors Associated With the Formation of Nasal polyp-a Case Control and Descriptive Study
NCT01278719 ·Status: UNKNOWN
-
Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis
NCT02743871 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps
NCT02170337 ·Status: COMPLETED ·Phase: PHASE1
-
An Open-label Study to Identify Molecular Markers of Steroid Resistance
NCT01616160 ·Status: TERMINATED ·Phase: PHASE4
-
Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP
NCT05672030 ·Status: COMPLETED
-
The Sinonasal Microbiome
NCT06822725 ·Status: ACTIVE_NOT_RECRUITING
-
Omalizumab Efficacy in Patients With Refractory Nasal Polyps
NCT05405478 ·Status: UNKNOWN ·Phase: PHASE4
-
Medical Polypectomy and Predictors of Response
NCT00788749 ·Status: COMPLETED ·Phase: PHASE4
-
The Study of GR1802 in Patients with Chronic Rhinosinusitis with Nasal Polyps
NCT05873803 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).
NCT05365841 ·Status: RECRUITING
-
Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps
NCT05009758 ·Status: RECRUITING ·Phase: NA
-
Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Extension Phase to Assess Safety
NCT01622569 ·Status: COMPLETED ·Phase: PHASE3
-
Rinitis y Sinusitis según la Gravedad Del Asma
NCT01513837 ·Status: COMPLETED
-
Predictive Factors in Chronic Rhinosinusitis With Nasal Polyps
NCT06459622 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Blown Nasal Secretion Measurements in Rhinosinusitis: Repeatability and Validity Compared to Nasal Lavage
NCT00292851 ·Status: COMPLETED
-
Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab Treatment
NCT05642806 ·Status: RECRUITING ·Phase: PHASE4
-
A Study of GR1802 in Participants With Chronic Sinusitis With Nasal Polyps
NCT06516302 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.
NCT05143502 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of SHR-1905 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps
NCT05891483 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma
NCT06069310 ·Status: ACTIVE_NOT_RECRUITING
-
Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia
NCT02217332 ·Status: COMPLETED ·Phase: PHASE2