Lean Muscle Function
NCT01616498 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24
Last updated 2017-03-14
Summary
This pilot study is designed to determine the relationship between intra-myocellular lipids and muscle contractility in fibers from obese and non-obese older adults. Obese participants are being recruited for an on-going weight loss intervention study and this application seeks approval to recruit and enroll a lean comparison group of non-obese older adults. The primary goal of this study is to characterize the contractile properties of single muscle fibers and whole muscle in healthy, non-obese individuals under the same recording conditions the investigators used for the obese population to begin to determine whether fat infiltration accounts for diminished force.
Conditions
- Single Muscle Fibers
Sponsors & Collaborators
-
Wake Forest University
lead OTHER
Principal Investigators
-
Barbara Nicklas, PhD · Wake Forest University Health Sciences
Eligibility
- Min Age
- 65 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-06-30
- Primary Completion
- 2013-09-30
- Completion
- 2013-11-30
Countries
- United States
Study Locations
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