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Effect of Stimulation of Dorsolateral Prefrontal Cortex on Language Control

NCT02289521 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2018-05-01

No results posted yet for this study

Summary

This study aims to evaluate the effect of stimulation of prefrontal regions on language performance (e.g. word translation and picture naming).

During the language tests, cortical activity will be registered using electroencephalography (EEG) which will provide supplementary information about the cerebral processus involved in language production and management of two languages in bilingual subjects.

Conditions

  • Language
  • Executive Dysfunction

Interventions

DEVICE

Transcranial Direct Current Stimulation

We will use a non-invasive, reversible transcranial direct current stimulation (tDCS) using a low-intensity electrical current. We will use Anodal and Sham tDCS. * Anodal: Active anodal electrode over F3 (EEG system) and return electrode over right supraorbital area. A 1.5mA current will flow between the electrodes for 20min. To decrease current-induced injuries, at the beginning, the current reaches from 0 to 1.5mA during 30 seconds (fade-in), and decreases from 1.5mA to 0 in 15 seconds at the end (fade-out). * Sham: The parameters mimics the A-tDCS (i.e. electrode placement, fade-in and current intensity), except the duration of stimulation: the current will reach to 1.5mA in 30 seconds (fade-in) and lasts only for 30 seconds (to give the initial sensation of stimulation).

Sponsors & Collaborators

  • Swiss National Science Foundation

    collaborator OTHER

  • University of Bern

    collaborator OTHER

  • University of Geneva, Switzerland

    collaborator OTHER

  • University of Fribourg

    lead OTHER

Principal Investigators

  • Jean-Marie Annoni, MD · University of Fribourg

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2015-08-31
Completion
2018-05-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02289521 on ClinicalTrials.gov