Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia

NCT01576185 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2016-05-17

No results posted yet for this study

Summary

These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML. Studying tissue samples from patients with cancer in the laboratory may help doctors learn more about cancer and how well patients will respond to treatment.

Conditions

  • Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies

Interventions

OTHER

laboratory biomarker analysis

Correlative studies

DRUG

quizartinib

Via gavage

DRUG

sorafenib tosylate

Via gavage

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH
  • Children's Oncology Group

    lead NETWORK

Principal Investigators

  • Sarah Tasian, MD · Children's Oncology Group

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2016-05-31
Completion
2016-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01576185 on ClinicalTrials.gov