Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia
NCT01576185 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2016-05-17
Summary
These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML. Studying tissue samples from patients with cancer in the laboratory may help doctors learn more about cancer and how well patients will respond to treatment.
Conditions
- Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies
Interventions
- OTHER
-
laboratory biomarker analysis
Correlative studies
- DRUG
-
quizartinib
Via gavage
- DRUG
-
sorafenib tosylate
Via gavage
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Children's Oncology Group
lead NETWORK
Principal Investigators
-
Sarah Tasian, MD · Children's Oncology Group
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-05-31
- Primary Completion
- 2016-05-31
- Completion
- 2016-05-31
Countries
- United States
Study Locations
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