Neurocircuitry of Autism- fMRI and Transcranial Magnetic Stimulation Studies
NCT01553240 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2017-01-13
Summary
This study uses functional brain imaging and noninvasive brain stimulation techniques to study the brain basis of developmental disorders like Autism Spectrum Disorder and Asperger Disorder. Functional magnetic resonance imaging (fMRI) and recently approved FDA treatment of depression, Transcranial magnetic stimulation (TMS) will be used to study the neurocircuitry of certain symptom clusters in developmental disorders.
Conditions
- Autism Spectrum Disorder
- Asperger Disorder
- Pervasive Developmental Disorder
Interventions
- DEVICE
-
TMS and functional MRI (Magstim)
single and paired pulse low frequency TMS. 3T structural MRI scans, amplitude modulated continuous arterial spin labeling( CASL) perfusion imaging sequence optimized for 3T is employed for perfusion MR scans using GE FAIR sequence for parallel imaging.
Sponsors & Collaborators
-
New York State Psychiatric Institute
lead OTHER
Principal Investigators
-
Alexandra Sporn, MD · NYPI, Columbia University
-
Sarah Lisanby, MD · NYPI, Columbia University
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-06-30
- Primary Completion
- 2010-06-30
- Completion
- 2010-06-30
Countries
- United States
Study Locations
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