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Increased Renal Oxygenation and Angiotensin Converting Enzyme Inhibition

NCT01545479 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2012-03-06

No results posted yet for this study

Summary

It is well established that renal hypoxia is associated with the development of renal injury. The purpose of this study is measure the alterations in renal blood oxygenation after angiotensin II converting enzyme inhibition. The understanding of kidney adaptive mechanisms to renin angiotensin system effects in healthy subjects will be useful for the early detection of renal disease and for the development of new therapies to decrease the progression of the disease and its consequences.

Conditions

  • Renal Disease

Interventions

DRUG

captopril 25mg

renal blood oxygenation after captopril

Sponsors & Collaborators

  • Instituto de Cardiologia do Rio Grande do Sul

    lead OTHER

Principal Investigators

  • MAntonieta Moraes, Dr · Instituto de Cardiologia do Rio Grande do Sul

Study Design

Allocation
NA
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
45 Years
Max Age
55 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2010-10-31
Completion
2010-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01545479 on ClinicalTrials.gov