MedTrace Logo

A Study of a Prebiotic, a Probiotic and a Synbiotic Upon the Gut Microbiota and Immune Response of Healthy Volunteers

NCT01545219 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2012-03-07

No results posted yet for this study

Summary

Healthy volunteers will be recruited to a study where they will be given four different treatments over a 28 week period. These treatments include: a prebiotic, a probiotic, a synbiotic (prebiotic + probiotic) and a placebo. Faecal samples, blood and saliva will be collected and analysed for changes in faecal microbial populations and selected immune responses.

Conditions

  • Gut Microbiota
  • Bowel Function
  • Immune Function
  • Plasma Lipids

Interventions

DIETARY_SUPPLEMENT

Prebiotic

8g/day xylo-oligosaccharide

DIETARY_SUPPLEMENT

Bi-07

10\^9 CFU B. lactis / day

DIETARY_SUPPLEMENT

Synbiotic

8g/day xylo-oligosaccharide + 10\^9 CFU Bi-07

DIETARY_SUPPLEMENT

Placebo

8g/day maltodextrin

Sponsors & Collaborators

  • Danisco

    collaborator INDUSTRY

  • University of Reading

    lead OTHER

Principal Investigators

  • Glenn R Gibson, BSc, PhD · University of Reading

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2009-09-30
Completion
2010-01-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01545219 on ClinicalTrials.gov