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Bone Marrow Aspiration Pain Study

NCT01524523 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2017-07-02

No results posted yet for this study

Summary

Background:

\- Many people feel pain during and after bone marrow aspiration (collection). Studies suggest that pain may be related to different kinds of inflammation, or the presence of nitric oxide (a normally occurring gas) in the body. Researchers want to study nitric oxide levels in the blood and breath before and after bone marrow collection. They will look at how these levels relate to feelings of pain.

Objectives:

\- To better understand pain related to having a bone marrow collection.

Eligibility:

\- Individuals at least 18 years of age who are enrolled in a study that requires bone marrow collection.

Design:

* Participants will be screened with a physical exam, medical history, and blood sample.
* Participants will provide study blood and breath samples to check nitric oxide levels. Participants will also have a test to measure skin sensitivity to heat and touch.
* During the collection, participants will keep track of their pain levels.
* After the collection, participants will keep track of any pain medications they take. They will also record if and when they eat any foods that contain nitrates for about 24 hours.

Conditions

  • Acute Pain
  • Gene Expression
  • Nitric Oxide

Sponsors & Collaborators

  • National Institutes of Health Clinical Center (CC)

    lead NIH

Principal Investigators

  • Wendy B Smith, Ph.D. · National Institutes of Health Clinical Center (CC)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-12-02
Completion
2013-06-27

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01524523 on ClinicalTrials.gov