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Retinal Adaptation to Intensified Insulin Therapy and Bariatric Surgery in Patients With Diabetes

NCT01517490 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2015-03-11

No results posted yet for this study

Summary

Retinal function is highly dependent on the glucose supply. Thus, functional adaptations occur in response to both acute and long-term changes in glycaemia.

The purpose of this study is to examine functional and metabolic aspects of retinal adaptation to long-lasting changes in glycaemic control in patients with diabetes. The adaptational phenomena will be characterized by electroretinography, dark adaptation, measures of retinal perfusion and oximetry as well as diabetic retinopathy grading and (OCT).

Conditions

Interventions

OTHER

Insulin pump

Insulin pump therapy

OTHER

Multiple daily insulin injections

Multiple daily insulin injections

PROCEDURE

Bariatric surgery

Pre-operative weight loss and bariatric surgery.

OTHER

Medical therapy for type 2 diabetes

Medical glucose-lowering therapy and non-surgical weight-lowering interventions.

Sponsors & Collaborators

  • Glostrup University Hospital, Copenhagen

    lead OTHER

Principal Investigators

  • Oliver Klefter, MD · Glostrup UH

  • Michael Larsen, Professor, DMSci · Glostrup UH

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2016-12-31

Countries

  • Denmark

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01517490 on ClinicalTrials.gov