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The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy

NCT05189353 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2023-11-01

No results posted yet for this study

Summary

The overall aim is to delineate the contribution of ghrelin to glucose tolerance after sleeve gastrectomy. The hypothesis is that decreased concentration of ghrelin after SG is of importance for improved insulin secretion and glucose tolerance seen after SG. The expectation is therefore that infusion of ghrelin will impair insulin secretion and glucose tolerance compared with a control day without ghrelin infusion.

Conditions

  • Bariatric Surgery Candidate
  • Glucose Metabolism Disorders

Interventions

OTHER

Ghrelin

Ghrelin infusion

OTHER

Placebo

Saline infusion

Sponsors & Collaborators

  • Institute of Biomedical Sciences, SUND, University of Copenhagen

    collaborator UNKNOWN

  • Hvidovre University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-01-14
Primary Completion
2023-06-26
Completion
2023-06-26

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05189353 on ClinicalTrials.gov