The Aim of the Study is to Check Whether Follicular Fluid Evaluation Using a Spectrophotometer Can Differentiate High Quality Oocytes From Low Quality Oocytes. Oocyte Quality Will be Defined Using GDF9, BMP15 and Oocyte Morphology.
NCT07329998 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2026-01-09
Summary
The aim of the study is to check whether follicular fluid evaluation using a spectrophotometer can differentiate high quality oocytes from low quality oocytes. Oocyte quality will be defined using GDF9, BMP15 and oocyte morphology. The correlation between cortisol levels in women and oocyte quality parameters will be estimated.
Conditions
- Oocyte Quality Assessment Using Spectrophotometer
Interventions
- PROCEDURE
-
Oocyte quality assessment using spectrophotometer
On the OPU (ovum pick-up) day the following blood biochemical markers will be measured as well- Blood interleukins 1-6, cytokine, hormone profile, lipid profile, cortisol. After collecting the oocytes- the Follicular fluid will be sent for the following tests- 1. mid-infrared spectrometry, 2. P, E2, testosterone, cortisol, cytokines, IL 1-6, lipids, fatty acids. 3. BMP-15, GDF-9 and HSPG2 4. GCMS-Gas Chromatography Mass Spectrophotometer
Sponsors & Collaborators
-
Hillel Yaffe Medical Center
lead OTHER_GOV
Study Design
- Allocation
- NA
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-09-22
- Primary Completion
- 2025-12-16
- Completion
- 2026-11-01
Countries
- Israel
Study Locations
More Related Trials
-
Modulation Contrast Microscopy Imaging for Oocyte Quality Assessment
NCT03683290 ·Status: UNKNOWN
-
Human Follicular Fluid Markers and Reproductive Outcomes in IVF
NCT05893238 ·Status: UNKNOWN
-
The Difference Seen in Granulosa Cells and Immature Oocytes in IVF Treated Patients Sorted by Body Mass Index (BMI)
NCT03020173 ·Status: UNKNOWN
-
Establishing a Minimum Predictive Threshold Follicular Size and Oocyte Retrieval in ICSI Cycle
NCT07331493 ·Status: NOT_YET_RECRUITING
-
In Vitro Maturation of Immature Oocytes
NCT00480337 ·Status: COMPLETED ·Phase: NA
-
Multi-factorial Analysis of the Follicular Fluid Milieu to Explore the Discrepant Effect of Follicular Fluid Endometrial Flushing on Outcome of Assisted Reproduction Trial
NCT02468258 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Comparison of Follicle Diameter on hCG Day and Follicle Diameters on OPU (Oocyte Pick up) Day and the Effect of Follicle Diameters on Embryo Development and Pregnancy Outcomes
NCT04679688 ·Status: UNKNOWN ·Phase: NA
-
Data Collection Protocol for the Development of CHLOE-OQ, an AI Model for Assessing Oocytes Quality.
NCT06928337 ·Status: RECRUITING
-
Sperm Micro-swim up Technique; Process and Select in the Same Dish: a Sibling-oocyte-split Design
NCT05113225 ·Status: COMPLETED ·Phase: NA
-
The Cytogenetic Constitution of Embryos Resulting From Immature Oocytes (M1)
NCT00544531 ·Status: COMPLETED
-
Oocyte Cryopreservation: Evaluation of an Oocyte Freezing and Thawing Technique
NCT00713869 ·Status: UNKNOWN
-
Evaluation of Some Trace Elements in Follicular Fluid in ICSI Cases and Their Effect on ICSI Outcomes
NCT06719817 ·Status: RECRUITING
-
Evaluation of the Role of Follicular Sensitivity Index in the Prediction of IVF/ICSI Outcome
NCT02317978 ·Status: COMPLETED
-
Cleavage Pattern of Embryos and Oxidative Parameters
NCT03791931 ·Status: UNKNOWN ·Phase: NA
-
Automated 3D (SonoAVC) Versus 2D Ovarian Follicles Assessment in IVF Cycles: a Randomized Controlled Trial
NCT01723267 ·Status: COMPLETED ·Phase: NA
-
Egg Freezing Pilot Study
NCT00839839 ·Status: COMPLETED ·Phase: NA
-
Egg Quality Assessment
NCT06609421 ·Status: SUSPENDED
-
Identifying Expression Markers of Cumulus Cells to Identify Oocyte Developmental Potential Through a Maturation Analysis
NCT02230449 ·Status: COMPLETED
-
A Comparative Study of Sibling Oocytes: ICSI vs. the IMSI Sperm Selection Method
NCT03240276 ·Status: UNKNOWN ·Phase: NA
-
Oocyte Cryopreservation
NCT01232972 ·Status: TERMINATED ·Phase: NA
-
Comparison of 2 Different Flow Rates During Oocyte Retrieval
NCT06019494 ·Status: COMPLETED ·Phase: NA
-
Investigational Oocyte Cryopreservation for Medical and Non Medical Indications
NCT04616417 ·Status: COMPLETED ·Phase: NA
-
Anti COVID-19 Antibodies in Follicular Fluid and Spermatic Fluid
NCT04822012 ·Status: UNKNOWN
-
Association Between Oxidative Parameters in Fertilization Medium of Cumulus Oocyte Complex and Outcome in IVF
NCT03382002 ·Status: UNKNOWN
-
Is There a Difference in Oocyte Quality? A Comparison of Two Aspiration Needle Gauges
NCT02749773 ·Status: UNKNOWN ·Phase: NA