Functional Imaging of Psychic Pain

Summary

Suicidal behaviour (SB) represents a major public health problem, costing life in more that one million people every year worldwide. Even if SB is considered as a consequence of social adversity and depression, these stress factors are often necessary but not sufficient to explain the occurrence of a suicidal act. A preliminary study suggests that an increased perception of psychic pain during a major depressive disorder increases the risk of suicide behaviour. The investigators aimed to investigate the relationship between social exclusion (a classic trigger of psychic pain) and SB and improve our knowledge about the physiopathology of this domain.

Conditions

• Suicide, Attempted
• Mood Disorder

Interventions

BEHAVIORAL

Assessment of personality traits

suicide behaviour , psychic pain, social exclusion, decision making...

BEHAVIORAL

Assessment of suicidal act

suicide behaviour , psychic pain, social exclusion, decision making...

BEHAVIORAL

Assessment of depression

suicide behaviour , psychic pain, social exclusion, decision making...

PROCEDURE

Cyber ball game

functional neuroimaging

PROCEDURE

Iowa Gambling Task

functional neuroimaging

PROCEDURE

Microcomputer

functional neuroimaging

PROCEDURE

blood sample

blood sample

Sponsors & Collaborators

• University Hospital, Geneva

  collaborator OTHER

• Institut National de la Santé Et de la Recherche Médicale, France

  collaborator OTHER_GOV

• University Hospital, Montpellier

  lead OTHER

Principal Investigators

• Philippe PC Courtet, Professor(MD-PhD) · University Hospital, Montpellier

Study Design

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

50 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2010-05-31

Primary Completion

2014-08-31

Completion

2014-12-31

Countries

• France

Study Locations