Cognitive and Psychological Disorders After Severe COVID-19 Infection

Summary

As COVID-19 pandemic is still ongoing, patients follow-up begins to reveal cognitive and psychological disorders. There are not yet well described, neither their physiopathology. This study will consist in the detection and characterization of cognitive and psychological impairments in young patients under 65 years of age who have been hospitalized more than 72 hours for a severe COVID-19 infection.

Conditions

• COVID 19

Interventions

DIAGNOSTIC_TEST

Cognitive assessment

Complete cognitive and psychological assessment

DIAGNOSTIC_TEST

Imaging

Brain MRI Optional: Brain FDG PET (Brain positron emission tomography with F-18 fluorodeoxyglucose)

DIAGNOSTIC_TEST

Routine care

Electroencephalogram (EEG) Optional: polysomnography, lumbar puncture

OTHER

Psychiatric evaluation

Psychiatric consultation if necessary

OTHER

Psychiatric evaluation

Psychiatric consultation if necessary (before the end of their participation in the study)

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Besancon

  collaborator OTHER

• University Hospital, Strasbourg, France

  collaborator OTHER

• Centre Hospitalier Régional Metz-Thionville

  collaborator OTHER

• Centre hospitalier Epinal

  collaborator UNKNOWN

• Hopitaux Civils de Colmar

  collaborator OTHER

• Central Hospital, Nancy, France

  lead OTHER

Study Design

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-08-23

Primary Completion

2023-09-27

Completion

2023-09-27

Countries

• France

Study Locations