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Vitamin D and Physical Activity on Bone Health

NCT01419730 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 191

Last updated 2026-04-07

No results posted yet for this study

Summary

This research will examine the effectiveness of vitamin D or placebo (the placebo is a tablet that looks like Vitamin D study drug, but has no Vitamin D study drug in it), with and without physical activity (walking and progressive resistance exercise), in treating bone loss in women who have undergone treatment for breast cancer. The investigators would also like to find out if the physical activity program improves cardiovascular fitness, energy expenditure, muscular strength, muscle mass, and balance. One hundred five (105) subjects are expected to take part in this study. The investigators don't know if bone loss in breast cancer survivors should be treated differently than bone loss in other women.

Conditions

  • Bone Metabolism Biomarkers
  • Bone Mineral Density
  • Physical Fitness

Interventions

DRUG

Vitamin D3

Vitamin D3 50,000 IU

BEHAVIORAL

Physical Activity

Progressive walking and resistance band exercise prescription for a period of 24 weeks

Sponsors & Collaborators

  • University of Rochester

    lead OTHER

Principal Investigators

  • Luke J Peppone, PhD, MPH · University of Rochester

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2024-12-30
Completion
2026-12-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01419730 on ClinicalTrials.gov